PROPOLEOS Y COLESTEROL
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Items 1 - 4 of 4 |
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1: J Ethnopharmacol. 2005 Nov 14; [Epub ahead of print] |
Propolis:
Effect of different concentrations, extracts and intake period on seric biochemical variables.
Mani
F, Damasceno HC, Novelli
EL, Martins
EA, Sforcin
JM.
Department of Chemistry and Biochemistry, Biosciences Institute, UNESP,
18600-000 Botucatu, SP,
Propolis is a resinous substance produced by
honeybees that possesses many biological activities, such as
antitumor, antioxidant, antimicrobial,
anti-inflammatory, and immunomodulatory, among
others. The purpose of the present study was to investigate the biochemical
profile of propolis-treated rats to observe whether propolis might lead to side effects after administration.
Three different treatments were analyzed: (1) rats were treated with different
concentrations of propolis (1, 3 and 6mg/kg/day)
during 30 days; (2) rats were treated with 1mg/kg/day of ethanolic
or water extracts of propolis (EEP, WEP) during 30
days; (3) rats were treated with 1mg/kg/day of ethanolic
extract of propolis during 90 and 150 days. Our
results demonstrated no alterations in the seric
levels of cholesterol, HDL-cholesterol, total lipids, triglycerides and in the
specific activity of aminotransferases (AST) and
lactic dehydrogenase (LDH) of propolis-treated
groups when compared to controls. On the basis of our findings, since propolis does not induce any significant change in seric parameters, it is claimed that long-term
administration of propolis might not have any cardiac
injury.
PMID: 16293383 [PubMed
- as supplied by publisher]
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2:
Pharmacol Res. 2005 Feb;51(2):147-52. |
Effects of propolis
on blood glucose, blood lipid and free radicals in rats with diabetes mellitus.
Fuliang HU, Hepburn HR, Xuan H, Chen M, Daya S, Radloff SE.
College of Animal Science,
The effects of ethanol (EEP) and water (WSD) extracts of propolis
collected from north
PMID: 15629260 [PubMed
- indexed for MEDLINE]
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3:
Fitoterapia.
2002 Nov;73 Suppl 1:S1-6. |
Propolis, an
old remedy used in modern medicine.
Castaldo S, Capasso F.
Department of I.N.P.S. of
Propolis is one of the few natural remedies that has maintained its popularity over a long period of time.
The pharmacologically active molecules in the propolis
are flavonoids and phenolic
acids and their esters. These components have multiple effects on bacteria, fungi
and viruses. In addition, propolis and its components
have anti-inflammatory and immunomodulatory
activities. Moreover, propolis has been shown to
lower blood pressure and cholesterol levels. However, clinical studies to
substantiate these claims are required.
Publication Types:
·
Review
PMID: 12495704 [PubMed - indexed for MEDLINE]
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4: Eksp Klin Farmakol. 1994 Jul-Aug;57(4):39-42. |
[The liver-protective properties of the pediatric
drug form of propolis in animals of different age
groups]
[Article in Russian]
Drogovoz SM, Tikhonov AI, Slyshkov VV, Sal'nikova SI.
The pharmacological activity of a pediatric formulation
of the phenolic hydrophobic drug propolis
was studied in the experiments on albino rats of various age
with toxic liver damages of various duration and in acute hepatic ischemia. In
all models of hepatic abnormalities, the drug was found to show antioxidative properties which were moderate (30-60%). In
addition, there were improvements in hepatic secretion of bile, cholic acids, and cholesterol. On the other hand, the
membrane-stabilizing effect of the drug was exerted in not all the tested
models of hepatic damage.
PMID: 7950783 [PubMed
- indexed for MEDLINE]