PROPOLEO Y DIABETES
| Items 1 - 6 of 6 |
One page. |
| 1: Clin Biochem. 2005 Feb;38(2):191-6. |
Effects of caffeic acid phenethyl
ester on lipid peroxidation and antioxidant enzymes
in diabetic rat heart.
Okutan
H, Ozcelik
N, Yilmaz
HR, Uz E.
Department of Cardiovascular Surgery,
OBJECTIVES: The risk for cardiovascular disease is significantly high in diabetes
mellitus. Experimental evidence suggests that oxidative stress plays a dominant
role in the pathogenesis of diabetes mellitus. Caffeic
acid phenethyl ester (
| 2: Pharmacol Res. 2005 Feb;51(2):147-52. |
Effects of propolis on blood glucose,
blood lipid and free radicals in rats with diabetes mellitus.
Fuliang HU, Hepburn
HR, Xuan H, Chen
M, Daya S, Radloff SE.
College of Animal Science,
The effects of ethanol (EEP) and water (WSD) extracts of propolis
collected from north
PMID: 15629260 [PubMed
- indexed for MEDLINE]
| 3: Asia Pac J Clin Nutr. 2004;13(Suppl):S66. |
Effect of combined
propolis-ethanol-extract and Shaoyao-Gancao-tang
on blood sugar levels in rabbits with alloxan induced
experimental diabetes.
Wang
NZ, Li D.
Dept of Food Science,
Background - Propolis, a bee-hive product, has been
used as a Chinese folk medicine for thousand years, with reported beneficial
effects on various clinical conditions. Shaoyao-Gancao-tang,
a prescription Chinese Medicine, is a mixture of the water extract of liquorice
(Radix Glycyrrhizac) and peony (Paeonialaciflora)
roots. Objective - To investigate the effect of combined propolis-ethanol-extract
and Shaoyao-Gancao-tang (PSG) on blood sugar levels
of rabbits following alloxan induced experimental
diabetes. Design - PSG was prepared as a 1:1 mixture of propolis-ethanol-extract
and water extract of liquorice and peony roots. Fasting (8 h) blood sugar
> 180mg/mL was considered as experimental diabetes after rabbits were treated
with 100mg/kg of 5% alloxan for 72 h. Blood sugar
levels of the diabetic rabbits were measured after they were given a 0.3g/kg
oral dose of PSG (n=8) or propolis (n=8) at 6 and
24 h, respectively. A control group of diabetic rabbits (n=8) had no PSG or
propolis administered and were tested at the same time points.
Outcomes - Compared with control group, diabetic rabbits treated with PSG
or propolis showed a significant reduction in blood
sugar levels at 24 h (P<0.05), and PSG was more potent than propolis alone. Conclusions - The results indicated that propolis-ethanol-extract has a beneficial effect on reduction
of blood sugar levels in alloxan induced diabetic
rabbits, and may have a synergistic effect with Shaoyao-Gancao-tang.
PMID: 15294555 [PubMed - in process]
| 4: Altern Ther Health Med. 2004 May-Jun;10(3):78-9. |
Antihyperglycemic effects of propolis
mixed with mulberry leaf extract on patients with type 2 diabetes.
Murata K, Yatsunami
K, Fukuda
E, Onodera
S, Mizukami
O, Hoshino
G, Kamei
T.
Publication Types:
· Letter
PMID: 15154157 [PubMed - indexed for MEDLINE]
| 5: J Agric Food Chem. 2004 May 19;52(10):3083-8. |
Identification of metabolites in plasma and urine of Uruguayan propolis-treated
rats.
Kumazawa S, Shimoi K, Hayashi K, Ishii T, Hamasaka T, Nakayama T.
Laboratory
of Functional Food Science and COE Program in the 21st Century,
Propolis is a resinous substance collected by honeybees from various plant
sources. It is extensively used in food and beverages to improve health and
prevent diseases such as heart disease, diabetes, and cancer. To investigate
the absorption and metabolism of the components in propolis,
in the present study, we administered ethanol extracts of Uruguayan propolis (poplar type propolis)
orally to rats and analyzed their plasma and urine by high-performance liquid
chromatography with photodiode array and mass spectrometric detection. After
deconjugation of the components by beta-glucuronidase/sulfatase
treatment of the specimen, pinobanksin 5-methyl
ether, pinobanksin, kaempferol,
chrysin, pinocembrin,
and galangin were detected in plasma of rats orally administered
propolis. These compounds were detected also in
urine after beta-glucuronidase/sulfatase treatment.
Furthermore, pinobanksin 5-methyl ether, pinobanksin, chrysin, pinocembrin, and galangin were present
in the urine also in free form. These results suggest that flavonoids in propolis are metabolized
and circulate in the body after oral administration of propolis.
PMID: 15137857 [PubMed
- indexed for MEDLINE]
| 6: Biochem Pharmacol. 1983 Apr 1;32(7):1141-8. |
Flavonoids, a class
of natural products of high pharmacological potency.
Havsteen B.
A review has been presented of the biochemistry and pharmacology of a class
of natural products, the flavonoids. These substances
which are widely distributed in the plant kingdom and present in considerable
quantities in common food products, spices and beverages have in a concentrated
form (Propolis) been used since ancient times by physicians and
laymen to treat a great variety of human diseases but they have yet to pass
the tests of modern, controlled, clinical experimentation. An attempt has
been made to present the fundamental evidence from the basic biological sciences which is required to stimulate the interest of the
clinicians in this new field. The few existing reports on the careful pharmacodynamic, pharmacokinetic and clinical studies which
have been made have been summarized to provide a basis for a full-scale investigation
of the therapeutic potential of flavonoids.
Publication Types:
· Review
PMID: 6342623 [PubMed - indexed for MEDLINE]